Isostructural Self-Assembly of 2′-Deoxyguanosine Derivatives in Aqueous and Organic Media

نویسندگان

  • Marilyn García-Arriaga
  • Gerard Hobley
  • José M. Rivera
چکیده

We report the self-assembly of a hydrophilic 8-(m-acetylphenyl)-2'-deoxyguanosine (mAG) derivative into a discrete and thermally stable hexadecameric supramolecule in aqueous media. We demonstrate that this hexadecamer is isostructural to the one formed by a related lipophilic derivative in organic media. This mAG moiety represents a rare example of a small-molecule recognition motif that is capable of assembling isostructurally and with high fidelity in both organic and aqueous media.

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عنوان ژورنال:

دوره 130  شماره 

صفحات  -

تاریخ انتشار 2008